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Chronic Kidney Disease and Your Loved Ones

By Irene B Perez

When my nephrologist told me that I have impaired kidneys, I tried hard to control myself. I thought of my dad who underwent kidney hemodialysis. Instantly, I had a million questions. I am only 30 years old, how many years will I have left if I have kidney? I do not have any kidney problem symptoms or signs of renal insufficiency. Is there a kidney disease solution? How will this affect my family?

Having impaired kidney function does not only affect the person who has it but it also affects his loved ones, in many ways. It has a physical, emotional and financial impact on the whole family.

Kidney disease takes a toll on the family physically. My mother and mother in law took care of their husbands full time. My mother in law even resigned from her job as a teacher because my father in law had to go to the hospital three times a week or more for treatment of kidney. A dialysis session could last 4-5 hours and his schedule could be as early as 6 in the morning to late at night. In my father's case, more time is sometimes required as he went to a government nephrology hospital and there are a lot of kidney patients on queue. You can imagine the time and effort required to take them to and from the hospital. Everyone in the family has to coordinate their schedules to fit the dialysis treatments. There is also a proper kidney disease diet to be followed which in a way influences how the whole family should eat. But with proper time management and support, kidney treatments and living a life with kidney disease can run smoothly and stress free (or lesser stress at least).

Having a member of the family with end-stage kidney was as an emotional roller coaster ride for all of us. We went through the various stages from denial, to crying modes and finally acceptance. With proper awareness of the nature of kidney insufficiency and the possibility to restore kidney function or cure kidney disease with this book, we now look forward to a better future.

It is undeniable that having a kidney disease from kidney stones to chronic renal disease is expensive. You are fortunate if your health care provider covers nephrology treatments. My husband (boyfriend back then) and I decided to move to a metropolitan city to look for better paying jobs and earn enough to pay for our parents' treatments for kidney problems. However, as they say, there is always a reason for everything. Having both fathers undergoing dialysis is probably a sign from the heavens that we are meant for each other! We found good paying jobs, got married, found great friends and started our new family in this new city away from home.



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Heal Your Kidney Disease

By Warren Koh

The kidneys are part of the urinary system and they are responsible for cleansing the blood of excess fluid and waste. These organs also help to regulate blood pressure and maintain the balance of minerals in the blood. When they get damaged, for whatever reasons, it causes a build up of fluids in your body. This leads to kidney disease, which is commonly recognized, by the following symptoms or some of them:

Ankle Swelling
Vomiting
Insomnia or Lack of Sleep
Weakness
Shortness of Breath
Fatigue
Depression
Loss of Appetite
Low Back Problems
Skin Itching
Anemia
Sore Muscles
Headaches
High Creatine, Potassium and Urea Levels

Most of the time kidney disease is treated with drugs, dialysis or worse kidney transplant.

We come across an exciting Reverse Impaired Kidney Program, while helping our aunt, who was suffering from polycystic kidney disease but, not anymore, searching for a kidney diet.

A second generation qualified Naturopath and member of the Australian Natural Medicine Society, spent 8 years on researching and investigating from western modern science and way back to Asia ancient remedies to help his wife from advanced kidney failure. Finally he developed the Kidney Disease Solution and save his wife.

The solution does not use those potentially harmful drugs and other toxins that are prevalent in everyday living. Instead, it uses a multi-pronged approach such as;

Nutrition
Specific herbs
Minerals and vitamins
Relaxation and meditation
Balanced lifestyle
Gentle, regular exercise

4 Phase Healing Protocol unique to kidney disease.

You can avoid dialysis, you'll find that your skin start to turn soft and smooth, feeling fresh and energetics waking up in the morning, symptoms start to disappear one by one.

Improve your quality of life if you are already on dialysis and even improve kidney function during end stage renal failure without the use of drugs.
We are able to see the changes on my aunt, when she went through the program.

Her appetite improved.
No more dizzy and dumpy.
The color and smells of her urine back to normal dramatically.
She able to manage her stress.
Her doctor stops the EPO jab as her red blood cells return to normal.
Her creatine gone down from 1100 to 800.

His program includes the following:

Kidney Repair Toolkit of natural remedies on how to repair damage kidney.
Treatment Plan, step-by-step guide to eradicate the root cause of your kidney problem.
Simple to follow solution to improve kidney function.
Nutrition Plan, what to eat and what not to.
6 essential rules you must know before exercising.
Stress Management; learn to relax, as stress will cause kidney failure.
Email Support to Answer Questions
And more...

Depending on your circumstances, you can ease your symptoms, repair your kidneys completely or at very least improve your kidney help in some way.


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Staying Fit With Chronic Kidney Diseases

By Oladeji Morenikeji

Kidneys are two vital organs that play major roles in the body. They are responsible for the removal of waste products and excess fluid from the blood as urine. The kidneys also produce and regulate hormones, which control blood pressure and stimulate the production of red blood cells. Some people can have kidney disease and not be aware of it because the early signs can be very subtle until the disease is advanced.

Kidney disease can take many years to go from chronic kidney disease (CKD) to kidney failure. As the disease progresses the symptoms become more obvious and the patient begin to notice significant discomforts when urinating; if able at all urine may come very dark or bloody. Although some people with chronic kidney disease live throughout their lives without ever reaching kidney failure. Chronic kidney disease is a process during which kidney tissue is destroyed over a long period of time.

There are many different symptoms of kidney disease, this include symptoms of just feeling sick and weak, while some comes inform of infection or kidney stones. But most people do not usually feel sick until later stages when the kidneys are no longer capable of filtering sufficient volume of blood per minute.

Common signs and symptoms of kidney diseases

1, Weakness and tiredness or fatigue
2, frequent urination especially at nights
3, swelling of face, arms, legs and sometimes the whole body
4, Pain at the back just below the ribs
5, nausea and vomiting
6, itching of skin
7, pale skin that bruises easily
8, muscular twitches, cramps and pain
9, loss of appetite
10, burning sensation while urinating

It should be noted that kidney disease can strike anyone and that people suffering from chronic kidney diseases are treated by dialysis or kidney transplant after medication and dietary changes can no longer control these symptoms.

Dialysis Treatment - this is a safe and effective replacement for lost kidney function and does not improve the functions of the kidneys. However, once dialysis starts the patient will notice a remarkable improvement, as many of the symptoms will reduce or completely resolved. There are two different types of dialysis (1) Haemodialysis (2) Peritoneal dialysis.

1, Haemodialysis - is the type of dialysis treatment that cleanses the blood from waste and excess fluid that built up. During haemodialysis the blood travels through soft tubes to a dialysis machine where it goes through a special filter called a dialyzer or artificial kidney. As the blood is cleansed, it returns to the blood stream.

2, Peritoneal - here the blood does not travel to a machine, but it cleaned inside the body. The lining of the abdomen (peritoneum) acts as a natural filter and a cleansing solution called dialsate is passed into the abdomen through a soft tube called catheter. The waste and excess fluid is then passed from the blood into the cleansing solution. After several hours the used solution is drained from the abdomen and exchanged with fresh cleansing solution to begin the process again.

Kidney transplant - this involves taking a kidney from the body of one person and implanting it surgically into the body of someone with kidney failure. The kidney may come from someone who has died or from a living donor who may be close relative, spouse, friend or someone who wished to donate a kidney to anyone in need of a transplant. After the transplant, the patient will require taking special medications to prevent the body from rejecting the new kidney. Kidney transplant compared to dialysis can provide improved quality of life and life expectancy. Here the patient will not need to spend several hours every week having dialysis and will not require special dialysis diets and fluid limits. In all, the patient will feel better and have greater freedom.



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Hypertension (Blood Pressure) And Kidney Disease

By Robert S Taylor

High blood pressure is the second most leading cause of kidney failure, and end-stage renal disease (ESRD). Blood pressure measures the force of blood against the walls of the blood vessels. Extra fluid in the body increases the amount of fluid in blood vessels and makes blood pressure higher. Narrow, stiff, or clogged blood vessels also raise blood pressure.

High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then raise blood pressure even more. It's a dangerous cycle.

People with kidney failure opt to one of the two choices, either receive a kidney transplant or have regular blood-cleansing treatments called dialysis. Both options do not offer any assurance that the person will live a normal life. Dialysis is not a cure but a temporary solution to blood-cleansing and with transplant a regular medication is required and there are too many other complications. One of the things that may help avoid kidney failure is to keep the blood pressure under control.

Like high blood pressure early kidney disease is a silent problem and does not have any symptoms. People may have CKD but not know it because they do not feel sick. A person's glomerular filtration rate (GFR) is a measure of how well the kidneys are filtering wastes from the blood. GFR is estimated from a routine measurement of creatinine in the blood. The result is called the estimated GFR (eGFR).

Creatinine is a waste product formed by the normal breakdown of muscle cells. Healthy kidneys take creatinine out of the blood and put it into the urine to leave the body. When the kidneys are not working well, creatinine builds up in the blood. This reading alone can give a good indication if there is any abnormality about kidneys.

Another sign of CKD is proteinuria, or protein in the urine. Healthy kidneys take wastes out of the blood but leave protein. Impaired kidneys may fail to separate a blood protein called albumin from the wastes. At first, only small amounts of albumin may leak into the urine, a condition known as microalbuminuria, a sign of failing kidney function. As kidney function worsens, the amount of albumin and other proteins in the urine increases, and the condition is called proteinuria.

Many people need medicine to control high blood pressure. Several effective blood pressure medicines are available in modern and Alternate medicine. The most common types of blood pressure medicines doctors prescribe are diuretics, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), beta blockers, and calcium channel blockers. Diuretics, also known as "water pills," help a person urinate and get rid of excess fluid in the body. A combination of two or more blood pressure medicines may be needed to keep blood pressure below 130/80. In Ayurveda Sarpgandha, Vacha, Brahmi, Punarnava, are the herbs which can control mild to moderate blood pressure.

All these medicines may be required to keep the blood pressure low however, the bigger question is how to cure the disease? Transplant or Dialysis is not a cure but a temporary solution to the situation.



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Does a Kidney Disease Cure Exist? The Answer May Surprise You

By Duncan Capicchiano

If you or someone that you love has been diagnosed with kidney disease, the first question that probably comes to mind is "is there a cure?". Don't worry, there are a wide variety of options available to manage symptoms and improve kidney function.

Your kidneys are a very important part of your system as a whole. Every thirty minutes, all of the blood in your entire body passes through your kidneys to be filtered and cleaned. If your kidneys are not doing their job correctly, they will return toxic, waste-filled blood and other fluids back into the body. This can cause a whole host of problems. The kidneys are not independent organs closed off from the rest of your body's functions.

If you have issues with high blood pressure or diabetes, for instance, there is a huge likelihood that you will develop kidney problems if the aforementioned problems are not addressed. On the flip side, improperly functioning kidneys can cause a whole list of other problems, such as anemia and back pain. So it is important to look at the kidneys relationship to the body as a whole.

If you want to address kidney problems with western medicine, your doctor may prescribe a medicine such as an ACE inhibitor or an angiotensin II receptor blocker (ARB) to reduce the protein in your urine and to help manage high blood pressure. For infections, a round of antibiotics may do the trick to knock down bacteria build-up. In more extreme cases, dialysis or a full kidney transplant may be required to restore the efficiency of the kidneys. Traditional medicine can be effective at treating symptoms, but they may not address the fundamentals of what was causing the problem in the first place and in some cases pharmaceutical medication can actually contribute to kidney damage.

There are other methods of treating kidney disease, which can be used safely in combination with traditional remedies that address the root cause of kidney damage. For example, there are a wide variety of herbs that nature provides which act as kidney cleansers and tissue restoratives, effectively encouraging the kidneys to cleanse and heal themselves. Examples of cleansers are: corn silk, goldenrod, hydrangea and nettle leaf. Kidneys that are consistently cleansed do not have much of a chance to build up sediment, which turns to stones, or bacteria, which can lead to infections.

There have been many success stories resulting from a change to a more natural, unprocessed diet can help restore kidney health. Think about it - the kidneys function is to cleanse toxins and wastes. If you already have stressed kidneys, why would you knowingly put more 'toxins' such as acidic foods, sugar, preservatives, artificial colouring and flavourings into your body?

By eating fresh and natural foods, you give your kidneys a break, and cut down on their work load immensely. Foods such as sprouts, fish, seeds, asparagus, watermelon, green vegetables and whole grains all work to build up your kidney strength. You may find that watching your protein intake also helps give your kidneys a breather, though protein consumption is mainly based on what stage of kidney disease you are in.

There may not be one right answer that works for everyone or for a 'one size fits all' cure, however, if you suffer from kidney problems you should know all of your options available, whether they are through traditional medicine or natural medicine. Be open-minded, do your own research, and work with your doctor or naturopath to find a solution that works for you to restore your kidney health, as there are many people healing themselves right now and reversing their kidney disease naturally.



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Kidney Disease - The Solution of Diet For Your Kidney Disease

By MC Raflesia

People with kidney disease are more prone to heart disease and frequently require pursuit of a low-fat diet. The calorie intake on a daily basis requires keeping the person's nutritional status and avoiding the failure of body tissue. The person's weight and protein status ought to be observed habitually.

A good number of dialysis centers have put in dietitians who work with patients and physicians to teach the patients concerning their diet whilst on dialysis.

A low-protein diet is applied in people with abnormal kidney function to put off deterioration of their kidney disease. The diet is frequently low in sodium and potassium too. For a number of people on this diet, fluid constraint is essential too. In addition, if you suffer diabetes in company with kidney disease, a low-carbohydrate diet can be needed.

Low-protein diets can put off or decelerate the growth of some kinds of kidney disease. The sum of protein you may eat is founded on how well your kidneys are working and the sum of protein required to keeping good health.

Once you suffer kidney failure, the total of urine your body generates can drop off. The quantity of fluids you could drink every day is founded on the quantity of urine you generate in a 24-hour time. Other concerns on whether fluid should be constrained are the quantity of fluid you maintain, the height of sodium in your diet, whether you utilize diuretics, in addition to whether you suffer congestive heart failure.

A registered dietitian for nutrition information special to kidney disease, some even focus in kidney diets, must be referred by your kidney specialist. In advanced kidney disease, a low-protein diet could cause malnutrition and must simply be put into practice under the direction of a kidney specialist.



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Kidney Disease Can Have Disastrous Consequences, Alternative Health Care Options

By Bill Tallmon
Expert Author Bill Tallmon

This may surprise you but more than 300,000 Americans are on kidney dialysis to filter the impurities from their blood that their kidneys and bladder can no longer do. Those relegated to dialysis are seldom functional for more than a few years and die long before their time at an immense cost to society. This is a sad testament to our modern health system and its ability to teach how to prevent this man made diet related disease.

What causes kidney disease?

· Diet overload of food and drink
· Overeating of sugary foods
· Meats
· Carbonated drinks
· Caffeine
· Drug excess for pleasure, over the counter, and prescription drugs
· NSAIDs drugs (Advil, Motrin, and Aleve)
· Diabetes
· Antacids
· Heavy metal poisoning

Kidney stones have long afflicted mankind as they have discovered them in a 7000 year old mummy. (A kidney stone is an accumulated inorganic waste that form in the bladder and can become trapped in the urinary tract).

The incidence of kidney disease had risen each decade since world war two in the USA that is directly linked to:

· Low fiber intake
· High fats from large quantities of animal protein
· Sugary foods
· Excess alcohol
· Excess salt
· Excess food intake in general

Signs you may be afflicted with kidney problems:

· Pain full frequent urination
· Chronic lower back pain
· Chills and fever
· A dull ache in the back
· Nausea, fever, and vomiting.
· Fatigue
· Itching
· Bad taste in mouth
· Shortness of breath
· Extreme pain if a stone catches which results in excruciating radiating pain, followed by painful urination, blood in the urine

Natural health practice offers a way to eliminate the accumulation of inorganic materials in the body.

· Distilled water to dissolve and flush inorganic waste
· Kidney stone flush diet
· Kidney herbal flush
· Heat Therapy on lower back
· Fiber supplements

The various diets and herbal supplements are available both on line and in your health food store. Hydration is a key element in the health of kidneys. If you dry up chances are increased that you will suffer from this lifestyle disease.

• My biggest FEAR in life is becoming dependent.
• The idea of depending on my boss, a medical doctor, expensive insurance or the government for my health care did not feel right.
Are there Solutions?


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Risk Factors For Kidney Disease

By Aurther Shoko

Diabetes which often referred to as 'sugar' and hypertension are the leading causes of kidney disease. The damage done to kidneys occurs overtime and usually without the patient knowing it. Like high blood pressure the solution is found in regular testing of diabetes to establish its presence. As is apparent, each individual has two kidneys situated near the center of the back. Kidneys work by filtering blood using tiny blood vessels that remove waste and extra water then producing urine. Diabetes and hypertension damages these blood vessels and can then cause kidney ailment. Damaged kidneys may lead to a special type of hypertension called renovascular hypertension.

Kidney ailment from diabetes and high blood pressure does not go away. This is contrary to what most people wrongfully believe. Instead it gets worse over a period of time. If no attention is given it will lead to kidney failure which will require dialysis or transplant altogether. In terms of prevalence, in the United States African Americans are at high risk of kidney failure. This partly coincides with the already high prevalence of diabetes and hypertension in the African American community.

Damage to kidneys is established when doctors test a person's urine for protein. When kidneys have damage, protein escapes into urine as part of excretion. It follows that the sooner you are tested and the disease is caught the sooner you can take steps to keep your kidneys healthier for a longer time. Besides diabetes and high blood pressure another factors associated with kidney disease include having heart or cardiovascular disease or having your mother, father, sister or brother with kidney disease. This means in short having kidney ailment in the family raises your risk of developing kidney disease.

There are specific steps that can be taken to protect your kidneys. Apart from managing your diabetes and high blood pressure eating healthy is an important part of taking care of your kidney health. You will also need to stay active in addition to taking your medication as prescribed. Staying active keeps your blood pressure at bay. In fact doctors recommended sustained and regular exercise as a way of keeping your blood pressure under control as well as loosing weight. Taking medication as prescribed is extremely important. In fact in hypertension treatment taking medication inconsistently or out right abandon leads to refractory hypertension.

Just like hypertension, kidney ailment can be controlled if action is taken in advance of time. As mentioned earlier, regular testing is necessary in order to detect the problem early.



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Diabetes Can Develop to Kidney Disease

By See Ang
Expert Author See Ang

It is known that the more affluent a society, the incidence of diabetes is higher as compared to underdeveloped nations. So, it is the modern lifestyle and dietary that influences the Diabetes condition, causing people to suffer from this sickness.

For adult onset type 2 diabetic; study has shown that people who are over-weights and obesity, having higher than normal level of blood glucose; are facing a stronger risk. They are at a greater risk of health complications that involve damage to small blood vessels and nerves that can affect the kidneys, make damages to the kidneys known as (diabetic nephropathy), and leading to kidney failure that needs for dialysis.

What is a kidney disease? In layman terms; the kidneys fail their filtering capacity. Kidneys are complicated filtering organs and daily, they process our blood that was brought to the kidney through blood vessel and sift waste products and extra water out of the body. These wastes and water flow to the bladder through tubes and store in the bladder until it is released as urine.

For diabetes sufferers, glucose as a form of sugar stay in the blood stream instead of being used up by the cells as energy poses a problem to the kidney. The presence of sugar in the blood can act like poison damaging the Kidney slowly and silently. Eventually, after years the damage becomes apparent and it is known as diabetic Kidney disease. People with kidney failure have to undergo dialysis, an artificial blood-cleaning process, or transplantation to receive a healthy kidney from a donor to live.

Besides High Blood Pressure, Diabetes is one of the most common causes contributing to Kidney failure; accounting to almost half of new cases in the United States. From research, nearly 24 million people in the United States have diabetes and about 200,000 people are living with Kidney disease as a result of diabetes.

Today most diabetics apply management of blood glucose as a treatment; focusing to keep the glucose levels close to normal. Take drugs prescribed by physician, administration of insulin throughout the day and couple with dietary and physical activities to control the progression of getting the Kidney disease.

Ever wonder why seldom people ever talks about "curing diabetes?" Everyone seems to be contented with the finding to "control diabetes" or "live with diabetes" as a chronic sickness. No one is out to cure anyone because there is little monetary incentive in doing so. Instead, by keeping you sick and marginally pain free is the only solution for you these days. By doing so, you are being forced to buy all the same drugs over and over again.... If somebody shows you how to cure diabetes, then they would not have made much money of you, right?

I do not know about you, but for me I do not want to have to depend on some big drug company to keep me alive and comfortable so that I can give them more of my hard earned money every month, knowingly aware that there is no drug to "cure" diabetes.

In fact diabetes is a result of the disorder of our immune system. It occurs when the immune system is not active as normal to produce the required insulin. This phenomenon can be reversed.

One genius guy by the name of MATT TRAVERSO is doing exactly this; "Natural" cure and alternatives for treating diabetes! Besides, he has lectured and personally helped individuals beat the disease; he has proven to the point that the sufferers have actually confirm and re diagnoses as "no longer have the disease at all"

Therefore, if you are wise and want to find out this while it is possible for you to do so, then just visit this link now: "How to REVERSE DIABETES now!"



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Type 2 Diabetes - The Effects of Diabetes On The Kidneys

By Beverleigh H Piepers
Expert Author Beverleigh H Piepers

Diabetes continues to hold the distinction of being the number one cause of kidney failure. But many people are under the impression when diabetes is managed properly there is no harm being caused to the kidneys. Unfortunately, this is simply not always the case. Many people, Type 2 diabetics and non-diabetics alike, have the beginnings of kidney disease and don't even know it.

The problem lies in the fact kidney disease can surface in many different forms, and in many levels of severity. It is possible to have chronic kidney disease that does not morph into full-blown kidney failure. Further complicating matters is the fact there are many individuals who are not aware they even have some form of kidney disease.

In a person with diabetes, the kidneys start to work less efficiently because blood vessels in and round them become diseased. This takes place, partly due to free-radical damage, which is also the case in issues with the pancreas and heart.

Missing the signs of early kidney disease is easy unless you know what to look for. The importance of recognizing you have serious kidney problems is important because early detection means you can intervene quickly and save your kidneys.

Signs and symptoms of kidney problems: When kidney disease related to diabetes starts to occur, you will start to notice changes:

you may find you need to urinate less frequently, or you might find only a small amount comes out
your first sign of trouble could be swelling in your ankle
exhaustion: when your kidneys get tired, so do you
bad breath occurs when your kidneys stop filtering properly due to a build up of urea in your blood
flu-like symptoms due to uremia
itchy skin occurs due to your kidneys being unable to remove waste products from your bloodstream
flank pain

What does the future hold if kidney disease is not diagnosed and treated: Diabetes wreaks havoc on the kidneys by causing damage to the components of the kidney that filter out waste. Since the kidneys work to keep the right balance of water in your body it is important this balance be preserved. If the kidneys fail to perform this task, then it has to be done artificially or the individual would eventually die.This procedure is called dialysis and it involves being hooked up to a machine several times per week to allow it to filter the blood for you. About 40 percent of all dialysis patients have diabetes.

Dialysis is not meant to be a permanent solution to the problem. The best scenario is to perform a kidney transplant and replace the diseased kidney with a healthy one. Although there are two kidneys present, the human body is designed to work well with just one good kidney. Doctors have to keep a close eye on these cases since a common problem is not necessarily kidney disease itself, but the associated complications of diabetes that also occur, such as heart disease and damage to nerves.

The remarkable characteristic of kidney disease is that it is slow in progression. In fact, it is not uncommon for the disease to take up to 25 years before it has advanced to the stage of kidney failure. Typically, there are no ill effects of kidney disease within the first 10 years of Type 2 diabetes. Equally remarkable is the fact that as a diabetic advances past the 25 year marker of having diabetes, their probability of developing kidney disease actually decreases.


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the kidney disease solution kidney disease symptoms kidney disease polycystic kidney disease symptoms of kidney disease kidney failure kidney disease stages kidney disease treatment kidney diseases kidney disease solution kidney disease diet diet for kidney disease chronic kidney disease kidneys disease kidney stone treatment for kidney disease causes of kidney disease types of kidney disease signs of kidney disease what is kidney disease stages of kidney disease how to prevent kidney disease chronic kidney disease diet diabetic kidney disease kidney disease in dogs kidney disease symptoms in women reversing kidney disease what causes kidney disease cystic kidney disease chronic kidney disease stages kidney disease dialysis symptoms kidney disease renal kidney disease chronic kidney disease symptoms diets for kidney disease renal failure kidney polycystic kidney disease diet kidney function chronic kidney disease treatment kidneys renal disease kidney problems dialysis kidney disease stages kidney disease kidney stones cronic kidney disease renal failure symptoms kidney failure symptoms symptoms of kidney failure signs of kidney problems